FUNDING OPPORTUNITY

Image of text summarizing funding announcement

Announcement

Through the generous support of the H Foundation, Lurie Cancer Center (LCC) Members can apply for up to $10,000 to utilize any of the LCC supported Cores to drive research forward. Applicants must be using the chosen core for the first time or must not have used the core within the last year. The purpose of this RFA is to increase core usage by LCC members. Projects initiated with these awards should provide preliminary results for grant applications to external funding agencies for more long-term projects, such as NIH R21, R01 or larger grants. Application details are below.

Detailed information on CAMI equipment is available at https://cami.northwestern.edu/imaging-techniques/.

Applications will be submitted through the portal at https://competitions.fsm.northwestern.edu/grants/Cores. For questions and further information, please contact Jodi Johnson, PhD, Basic Research Program Coordinator at the Lurie Cancer Center, at jodi-johnson@northwestern.edu.

The deadline for applications is December 7, 2022.

Application Process

Before preparing an application, discuss project suitability and feasibility with facility staff by contacting the applicable core facilities, and make a statement in the application including the date of the consultation and name of the person with whom you spoke.

Proposals should be written in typeface no smaller than Arial 11 point, with 1-inch margins and should include the following sections:

  1. Title page including title, applicant names and affiliations, LCC program affiliation, and whether you are a new core user or have used the core in the past (date of past use must be more than 1 year ago).
  2. Project description
    No more than 2 pages, including figures. References can be on a separate page. This should be organized in the following sections:

    • Specific Aims
    • Significance including project’s relevance to cancer
    • Preliminary data or existing assays or model systems that are relevant to the proposed goals.
    • Research Plan
  3. Innovation
  4. No more than 200 words. Briefly describe the project’s unique aspects in the context of existing knowledge in the field
  5. Project continuation plan
  6. No more than 200 words. This brief unreferenced section should describe how the pilot project data will be used to achieve longer term research funding or continuation of the project.
  7. Include current NIH-style biosketches for all key personnel.

DO NOT SUBMIT A BUDGET.

Evaluation Process

Applications will be evaluated based on:

  • Cancer relevance of the project
  • Strength of ideas for use of the cores
  • Scientific merit, with particular attention given to innovation
  • Prospects for obtaining continued funding of the project

The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer’s Disease

Citation:

Viola KL, Bicca MA, Bebenek AM, Kranz DL, Nandwana V, Waters EA, Haney CR, Lee M, Gupta A, Brahmbhatt Z, Huang W, Chang T-T, Peck A, Valdez C, Dravid VP, Klein WL. The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer’s Disease. Frontiers in Neuroscience. 2022;15(1798). doi: 10.3389/fnins.2021.768646. PMID: 35046767

FUNDING OPPORTUNITY

Northwestern University’s Center for Advanced Molecular Imaging (CAMI) is offering pilot project funding for up to 10 projects/year for each of the next two years to researchers with nascent imaging projects that will benefit from CAMI expertise in preclinical imaging method development and refinement. Detailed information on CAMI equipment is available at https://cami.northwestern.edu/imaging-techniques/.

Selected projects will be funded for up to $5,000 for one year (in very special circumstances, up to $7,500) of direct costs for imaging studies performed in CAMI. Funds are designated for CAMI services and may not be used to purchase drugs, animals, or supplies. Budgets must allocate funding for method development and data analysis.

Applications will be submitted through the NUCATS Competitions platform, at https://competitions.fsm.northwestern.edu/grants/cami_pilot2022.

Full details of the RFP are available here (pdf link): CAMI Pilot Projects RFP 2022

Photocurable bioresorbable adhesives as functional interfaces between flexible bioelectronic devices and soft biological tissues

Citation:

Yang Q, Wei T, Yin RT, Wu M, Xu Y, Koo J, Choi YS, Xie Z, Chen SW, Kandela I, Yao S, Deng Y, Avila R, Liu TL, Bai W, Yang Y, Han M, Zhang Q, Haney CR, Benjamin Lee K, Aras K, Wang T, Seo MH, Luan H, Lee SM, Brikha A, Ghoreishi-Haack N, Tran L, Stepien I, Aird F, Waters EA, Yu X, Banks A, Trachiotis GD, Torkelson JM, Huang Y, Kozorovitskiy Y, Efimov IR, Rogers JA. Photocurable bioresorbable adhesives as functional interfaces between flexible bioelectronic devices and soft biological tissues. Nature materials. 2021. Epub 2021/07/31. doi: 10.1038/s41563-021-01051-x. PubMed PMID: 34326506.

Fully implantable and bioresorbable cardiac pacemakers without leads or batteries

Citation:

Choi YS, Yin RT, Pfenniger A, Koo J, Avila R, Benjamin Lee K, Chen SW, Lee G, Li G, Qiao Y, Murillo-Berlioz A, Kiss A, Han S, Lee SM, Li C, Xie Z, Chen YY, Burrell A, Geist B, Jeong H, Kim J, Yoon HJ, Banks A, Kang SK, Zhang ZJ, Haney CR, Sahakian AV, Johnson D, Efimova T, Huang Y, Trachiotis GD, Knight BP, Arora RK, Efimov IR, Rogers JA. Fully implantable and bioresorbable cardiac pacemakers without leads or batteries. Nat Biotechnol. 2021;39(10):1228-38. Epub 20210628. doi: 10.1038/s41587-021-00948-x. PubMed PMID: 34183859.

Wireless, battery-free, subdermally implantable platforms for transcranial and long-range optogenetics in freely moving animals

Citation:

Ausra J, Wu M, Zhang X, Vazquez-Guardado A, Skelton P, Peralta R, Avila R, Murickan T, Haney CR, Huang Y, Rogers JA, Kozorovitskiy Y, Gutruf P. Wireless, battery-free, subdermally implantable platforms for transcranial and long-range optogenetics in freely moving animals. Proceedings of the National Academy of Sciences of the United States of America. 2021;118(30). Epub 2021/07/25. doi: 10.1073/pnas.2025775118. PubMed PMID: 34301889; PMCID: PMC8325245.

Interested in joining CAMI?

We are seeking a Preclinical Imaging Technologist at the Research Tech 2 level to assist with rodent imaging studies for disease models and drug discovery using preclinical MRI, PET, SPECT, and CT scanners. You’ll assist with basic operation of scanners and other equipment (under a senior engineer’s guidance), image analysis, and routine lab maintenance.

For more information, and to submit an application, please see the Northwestern Careers posting. (Current NU employees, please use this link.)